Hae Young Chung Selected Research

Lung Neoplasms (Lung Cancer)

10/2022	MHY4571, a novel diarylcyclohexanone derivative, exerts anti-cancer activity by regulating the PKA-cAMP-response element-binding protein pathway in squamous cell lung cancer.
1/2018	Upregulation of P21-Activated Kinase 1 (PAK1)/CREB Axis in Squamous Non-Small Cell Lung Carcinoma.
11/2015	Novel dihydrobenzofuro[4,5-b][1,8]naphthyridin-6-one derivative, MHY-449, induces cell cycle arrest and apoptosis via the downregulation of Akt in human lung cancer cells.

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Hae Young Chung Research Topics

Disease

70	Inflammation (Inflammations) 04/2024 - 04/2002
36	Neoplasms (Cancer) 10/2022 - 02/2003
25	Melanoma (Melanoma, Malignant) 07/2022 - 02/2005
17	Insulin Resistance 01/2021 - 01/2013
15	Body Weight (Weight, Body) 11/2022 - 04/2002
13	Colonic Neoplasms (Colon Cancer) 09/2019 - 07/2004
12	Fibrosis (Cirrhosis) 04/2024 - 05/2013
10	Hyperpigmentation 01/2023 - 04/2011
7	Carcinogenesis 01/2023 - 06/2002
6	Colorectal Neoplasms (Colorectal Cancer) 12/2023 - 03/2014
6	Chronic Disease (Chronic Diseases) 03/2023 - 06/2007
6	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2020 - 02/2004
6	Alzheimer Disease (Alzheimer's Disease) 09/2016 - 02/2004
5	Parkinson Disease (Parkinson's Disease) 01/2022 - 01/2017
5	Type 2 Diabetes Mellitus (MODY) 01/2021 - 01/2013
5	Breast Neoplasms (Breast Cancer) 08/2017 - 09/2007
5	Hypoxia (Hypoxemia) 08/2017 - 11/2002
4	Colitis 01/2022 - 09/2014
4	Stomach Neoplasms (Stomach Cancer) 12/2018 - 06/2013
4	Obesity 08/2018 - 10/2010
4	Pigmentation Disorders (Ito Syndrome) 04/2015 - 01/2004
4	Experimental Melanoma 10/2013 - 02/2006
4	Atherosclerosis 12/2008 - 09/2005
3	Hyperlipidemias (Hyperlipidemia) 03/2024 - 12/2008
3	Asthma (Bronchial Asthma) 11/2023 - 01/2007
3	Liver Cirrhosis (Hepatic Cirrhosis) 08/2023 - 05/2013
3	Lung Neoplasms (Lung Cancer) 10/2022 - 11/2015
3	Diabetes Mellitus 10/2022 - 09/2002
3	Neuroinflammatory Diseases 11/2021 - 01/2019
3	Hyperinsulinism (Hyperinsulinemia) 10/2021 - 12/2014
3	Mitochondrial Diseases (Mitochondrial Disease) 01/2021 - 10/2008
3	Neuroblastoma 01/2019 - 01/2008
3	Melanosis (Freckles) 12/2018 - 10/2013
3	Fatty Liver 01/2018 - 08/2015
3	Cardiovascular Diseases (Cardiovascular Disease) 10/2015 - 09/2004
3	Prostatic Neoplasms (Prostate Cancer) 03/2014 - 05/2011
3	Hepatocellular Carcinoma (Hepatoma) 05/2012 - 02/2003
2	Hyperglycemia 03/2024 - 10/2022
2	Carcinoma (Carcinomatosis) 10/2022 - 07/2015
2	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 10/2022 - 01/2018

Drug/Important Bio-Agent (IBA)

28	Monophenol Monooxygenase (Tyrosinase)IBA 01/2023 - 02/2005
26	Melanins (Melanin)IBA 07/2022 - 01/2004
20	LipidsIBA 03/2024 - 06/2002
19	Proteins (Proteins, Gene)FDA Link 10/2023 - 04/2002
16	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 03/2023 - 10/2004
15	Transcription Factors (Transcription Factor)IBA 11/2020 - 10/2004
14	NF-kappa B (NF-kB)IBA 10/2017 - 11/2002
12	AntioxidantsIBA 01/2023 - 02/2004
12	Melanocyte-Stimulating Hormones (MSH)IBA 12/2018 - 04/2012
8	Glucose (Dextrose)FDA LinkGeneric 11/2020 - 09/2002
7	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 03/2023 - 10/2004
7	CytokinesIBA 07/2022 - 01/2007
7	Insulin (Novolin)FDA Link 11/2020 - 01/2013
6	Therapeutic UsesIBA 01/2022 - 05/2012
6	ResveratrolIBA 01/2018 - 12/2013
5	Reactive Oxygen Species (Oxygen Radicals)IBA 12/2023 - 02/2004
5	Sirtuin 1IBA 01/2023 - 01/2018
5	CaspasesIBA 10/2022 - 02/2006
5	FlavonoidsIBA 05/2014 - 09/2002
4	Histone Deacetylase InhibitorsIBA 12/2023 - 01/2010
4	Folic Acid (Vitamin M)FDA LinkGeneric 10/2023 - 10/2015
4	AcidsIBA 01/2020 - 01/2013
4	InflammasomesIBA 08/2018 - 08/2015
4	4-(6-hydroxy-2-naphthyl)-1,3-benzenediolIBA 08/2017 - 12/2013
4	Antineoplastic Agents (Antineoplastics)IBA 08/2017 - 01/2010
4	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 05/2017 - 01/2013
4	Betaine (C.B.B.)FDA Link 01/2017 - 10/2005
4	MHY-449IBA 11/2015 - 12/2012
3	Adenine FDA LinkGeneric 04/2024 - 11/2021
3	Peptide Hydrolases (Proteases)FDA Link 04/2024 - 01/2021
3	Histone Deacetylases (Histone Deacetylase)IBA 12/2023 - 01/2010
3	Dimethylnitrosamine (Nitrosodimethylamine)IBA 08/2023 - 05/2013
3	SirtuinsIBA 01/2023 - 11/2020
3	Ursolic AcidIBA 10/2022 - 03/2015
3	ChemokinesIBA 03/2022 - 01/2006
3	Phosphotransferases (Kinase)IBA 01/2022 - 01/2018
3	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 01/2022 - 02/2004
3	Peptides (Polypeptides)IBA 01/2022 - 02/2004
3	1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA 11/2021 - 01/2019
3	Neuroprotective AgentsIBA 01/2019 - 09/2016
3	1-Methyl-3-isobutylxanthine (1 Methyl 3 isobutylxanthine)IBA 12/2018 - 03/2018
3	Fatty Acids (Saturated Fatty Acids)IBA 01/2018 - 07/2017
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 08/2017 - 01/2010
3	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 05/2017 - 01/2013
3	Indicators and Reagents (Reagents)IBA 01/2017 - 09/2002
3	ApigeninIBA 12/2016 - 02/2003
3	N1- hydroxy- N8- (4- phenoxyphenyl)octanediamideIBA 08/2015 - 10/2012
3	Peroxynitrous Acid (Peroxynitrite)IBA 03/2014 - 06/2002
3	baicalinIBA 01/2013 - 09/2006
3	Nitric Oxide (Nitrogen Monoxide)FDA Link 09/2006 - 09/2005
2	Cisplatin (Platino)FDA LinkGeneric 04/2024 - 10/2022
2	Carbon Tetrachloride (Tetrachloromethane)IBA 08/2023 - 02/2016
2	Ascorbic Acid (Vitamin C)FDA LinkGeneric 11/2022 - 05/2010
2	Cyclic AMP Response Element-Binding Protein (Cyclic AMP-Responsive DNA-Binding Protein)IBA 10/2022 - 11/2018
2	Advanced Glycation End ProductsIBA 10/2022 - 02/2015
2	kojic acidIBA 07/2022 - 05/2022

Therapy/Procedure

11	Therapeutics 08/2021 - 06/2006
6	Chemoprevention 11/2020 - 01/2014
4	Oral Administration 08/2014 - 09/2002
3	Traditional Medicine (Folk Remedies) 11/2023 - 01/2017